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ECL: an exhaustive search tool for the identification of cross-linked peptides using whole database

BACKGROUND: Chemical cross-linking combined with mass spectrometry (CX-MS) is a high-throughput approach to studying protein-protein interactions. The number of peptide-peptide combinations grows quadratically with respect to the number of proteins, resulting in a high computational complexity. Wide...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Yu, Fengchao, Li, Ning, Yu, Weichuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874008/
https://ncbi.nlm.nih.gov/pubmed/27206479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1073-y
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