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Identification of cross-linked peptides from large sequence databases

We describe a method to identify cross-linked peptides from complex samples and large protein sequence databases. The advance was achieved by combining isotopically tagged cross-linkers, chromatographic enrichment, targeted proteomics, and a novel search engine called xQuest. This software reduces t...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rinner, Oliver, Seebacher, Jan, Walzthoeni, Thomas, Mueller, Lukas, Beck, Martin, Schmidt, Alexander, Mueller, Markus, Aebersold, Ruedi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719781/
https://ncbi.nlm.nih.gov/pubmed/18327264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1192
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