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Identification of cross-linked peptides from large sequence databases
We describe a method to identify cross-linked peptides from complex samples and large protein sequence databases. The advance was achieved by combining isotopically tagged cross-linkers, chromatographic enrichment, targeted proteomics, and a novel search engine called xQuest. This software reduces t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719781/ https://ncbi.nlm.nih.gov/pubmed/18327264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1192 |
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