Association of Distinct Variants in SORL1 With Cerebrovascular and Neurodegenerative Changes Related to Alzheimer Disease

BACKGROUND: Single-nucleotide polymorphisms (SNPs) in 2 distinct regions of the gene for the sortilin-related receptor (SORL1) (bounded by consecutively numbered SNPs 8−10 and 22−25) were shown to be associated with Alzheimer disease (AD) in multiple ethnically diverse samples. OBJECTIVE: To test th...

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Autores principales: Cuenco, Karen T., Lunetta, Kathryn L., Baldwin, Clinton T., McKee, Ann C., Guo, Jianping, Cupples, L. Adrienne, Green, Robert C., George-Hyslop, Peter H. St., Chui, Helena, DeCarli, Charles, Farrer, Lindsay A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719762/
https://ncbi.nlm.nih.gov/pubmed/19064752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneur.65.12.1640
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