Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease

Previous studies have shown association of single nucleotide polymorphisms (SNPs) in three contiguous genes (PON1, PON2 and PON3) encoding paraoxonase with risk of Alzheimer disease (AD). We evaluated the association of serum paraoxonase activity measured by phenyl acetate (PA) and thiobutyl butyrol...

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Autores principales: Erlich, Porat M., Lunetta, Kathryn L., Cupples, L. Adrienne, Abraham, Carmela R., Green, Robert C., Baldwin, Clinton T., Farrer, Lindsay A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034817/
https://ncbi.nlm.nih.gov/pubmed/20980077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.08.003
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