Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families

In vitro and animal model studies suggest that transthyretin (TTR) inhibits the production of the amyloid β protein, a major contributor to Alzheimer disease (AD) pathogenesis. We evaluated the association of 16 TTR single nucleotide polymorphisms (SNPs) with AD risk in 158 African American and 469...

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Main Authors: Cuenco, Karen T., Friedland, Robert, Baldwin, Clinton T., Guo, Jianping, Vardarajan, Badri, Lunetta, Kathryn L., Cupples, L. Adrienne, Green, Robert C., DeCarli, Charles, Farrer, Lindsay A.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930090/
https://ncbi.nlm.nih.gov/pubmed/19328595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2009.02.014
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