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Identification of Novel Candidate Genes for Alzheimer Disease by Autozygosity Mapping Using Genome Wide SNP Data From an Israeli-Arab Community

Alzheimer disease (AD) is highly prevalent in Wadi Ara, despite the low frequency of APOE ε4 in this genetically isolated Arab community in northern Israel. We hypothesized that the reduced genetic variability in combination with increased homozygosity would facilitate identification of genetic vari...

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Hlavní autoři: Sherva, Richard, Baldwin, Clinton T., Inzelberg, Rivka, Vardarajan, Badri, Cupples, L. Adrienne, Lunetta, Kathryn, Bowirrat, Abdalla, Naj, Adam, Pericak-Vance, Margaret, Friedland, Robert P., Farrer, Lindsay A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819807/
https://ncbi.nlm.nih.gov/pubmed/21098978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100714
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