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Boosting Antimicrobial Peptides by Hydrophobic Oligopeptide End Tags
A novel approach for boosting antimicrobial peptides through end tagging with hydrophobic oligopeptide stretches is demonstrated. Focusing on two peptides derived from kininogen, GKHKNKGKKNGKHNGWK (GKH17) and HKHGHGHGKHKNKGKKN (HKH17), tagging resulted in enhanced killing of Gram-positive Staphyloco...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719397/ https://ncbi.nlm.nih.gov/pubmed/19398550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011650 |
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