Boosting Antimicrobial Peptides by Hydrophobic Oligopeptide End Tags

A novel approach for boosting antimicrobial peptides through end tagging with hydrophobic oligopeptide stretches is demonstrated. Focusing on two peptides derived from kininogen, GKHKNKGKKNGKHNGWK (GKH17) and HKHGHGHGKHKNKGKKN (HKH17), tagging resulted in enhanced killing of Gram-positive Staphyloco...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Schmidtchen, Artur, Pasupuleti, Mukesh, Mörgelin, Matthias, Davoudi, Mina, Alenfall, Jan, Chalupka, Anna, Malmsten, Martin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Genomics, Proteomics, and Bioinformatics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719397/
https://ncbi.nlm.nih.gov/pubmed/19398550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011650
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki