The External Aldimine Form of Serine Palmitoyltransferase: STRUCTURAL, KINETIC, AND SPECTROSCOPIC ANALYSIS OF THE WILD-TYPE ENZYME AND HSAN1 MUTANT MIMICS

Sphingolipid biosynthesis begins with the condensation of l-serine and palmitoyl-CoA catalyzed by the PLP-dependent enzyme serine palmitoyltransferase (SPT). Mutations in human SPT cause hereditary sensory autonomic neuropathy type 1, a disease characterized by loss of feeling in extremities and sev...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Raman, Marine C. C., Johnson, Kenneth A., Yard, Beverley A., Lowther, Jonathan, Carter, Lester G., Naismith, James H., Campopiano, Dominic J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Enzyme Catalysis and Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719368/
https://ncbi.nlm.nih.gov/pubmed/19376777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.008680
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados