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Multifunctional Role of His(159)in the Catalytic Reaction of Serine Palmitoyltransferase

Serine palmitoyltransferase (SPT) belongs to the fold type I family of the pyridoxal 5′-phosphate (PLP)-dependent enzyme and forms 3-ketodihydrosphingosine (KDS) from l-serine and palmitoyl-CoA. Like other α-oxamine synthase subfamily enzymes, SPT is different from most of the fold type I enzymes in...

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Hlavní autoři: Shiraiwa, Yuka, Ikushiro, Hiroko, Hayashi, Hideyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786316/
https://ncbi.nlm.nih.gov/pubmed/19346561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808916200
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