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Multifunctional Role of His(159)in the Catalytic Reaction of Serine Palmitoyltransferase
Serine palmitoyltransferase (SPT) belongs to the fold type I family of the pyridoxal 5′-phosphate (PLP)-dependent enzyme and forms 3-ketodihydrosphingosine (KDS) from l-serine and palmitoyl-CoA. Like other α-oxamine synthase subfamily enzymes, SPT is different from most of the fold type I enzymes in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2786316/ https://ncbi.nlm.nih.gov/pubmed/19346561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808916200 |
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