Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel

The influenza A virus M2 protein (A/M2) is a homotetrameric pH-activated proton transporter/channel that mediates acidification of the interior of endosomally encapsulated virus. This 97-residue protein has a single transmembrane (TM) helix, which associates to form homotetramers that bind the anti-...

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Auteurs principaux: Ma, Chunlong, Polishchuk, Alexei L., Ohigashi, Yuki, Stouffer, Amanda L., Schön, Arne, Magavern, Emma, Jing, Xianghong, Lear, James D., Freire, Ernesto, Lamb, Robert A., DeGrado, William F., Pinto, Lawrence H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718339/
https://ncbi.nlm.nih.gov/pubmed/19590009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905726106
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