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A pH-dependent conformational ensemble mediates proton transport through the influenza A/M2 protein
The influenza A M2 protein exhibits inwardly rectifying, pH-activated proton transport that saturates at low pH. A comparison of high-resolution structures of the transmembrane domain at high and low pH suggests that pH-dependent conformational changes may facilitate proton conduction by alternately...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164293/ https://ncbi.nlm.nih.gov/pubmed/20968306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101229m |
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