Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus

The M2 proton channel from influenza A virus is an essential protein that mediates transport of protons across the viral envelope. This protein has a single transmembrane helix, which tetramerizes into the active channel. At the heart of the conduction mechanism is the exchange of protons between th...

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Bibliografiske detaljer
Main Authors: Acharya, Rudresh, Carnevale, Vincenzo, Fiorin, Giacomo, Levine, Benjamin G., Polishchuk, Alexei L., Balannik, Victoria, Samish, Ilan, Lamb, Robert A., Pinto, Lawrence H., DeGrado, William F., Klein, Michael L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930543/
https://ncbi.nlm.nih.gov/pubmed/20689043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007071107
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