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pH Induced Conformational Change of Influenza M2 Protein C-terminal Domain
The M2 protein from influenza A is a pH-activated proton channel that plays an essential role in the viral life cycle and serves as a drug target. Using spin labeling EPR spectroscopy we studied a 38-residue M2 peptide spanning the transmembrane region and its C-terminal extension. We obtained resid...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746938/ https://ncbi.nlm.nih.gov/pubmed/18754675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801315m |
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