Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

BACKGROUND: Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlated with adverse patient survival in cancer, we aimed at investigating a potentia...

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Hauptverfasser: Veeck, Jürgen, Wild, Peter J, Fuchs, Thomas, Schüffler, Peter J, Hartmann, Arndt, Knüchel, Ruth, Dahl, Edgar
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717119/
https://ncbi.nlm.nih.gov/pubmed/19570204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-217
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