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Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

BACKGROUND: Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlated with adverse patient survival in cancer, we aimed at investigating a potentia...

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Detalhes bibliográficos
Main Authors: Veeck, Jürgen, Wild, Peter J, Fuchs, Thomas, Schüffler, Peter J, Hartmann, Arndt, Knüchel, Ruth, Dahl, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717119/
https://ncbi.nlm.nih.gov/pubmed/19570204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-217
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