Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

BACKGROUND: Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlated with adverse patient survival in cancer, we aimed at investigating a potentia...

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Hlavní autoři: Veeck, Jürgen, Wild, Peter J, Fuchs, Thomas, Schüffler, Peter J, Hartmann, Arndt, Knüchel, Ruth, Dahl, Edgar
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717119/
https://ncbi.nlm.nih.gov/pubmed/19570204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-217
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