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Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer

INTRODUCTION: Endothelin (EDN) signalling plays a crucial role in cell differentiation, proliferation and migration processes. There is compelling evidence that altered EDN signalling is involved in carcinogenesis by modulating cell survival and promoting invasiveness. To date, most reports have foc...

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Main Authors: Wiesmann, Frank, Veeck, Jürgen, Galm, Oliver, Hartmann, Arndt, Esteller, Manel, Knüchel, Ruth, Dahl, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716502/
https://ncbi.nlm.nih.gov/pubmed/19527488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2319
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