Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening

INTRODUCTION: For early detection of breast cancer, the development of robust blood-based biomarkers that accurately reflect the host tumor is mandatory. We investigated DNA methylation in circulating free DNA (cfDNA) from blood of breast cancer patients and matched controls to establish a biomarker...

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Main Authors: Kloten, Vera, Becker, Birte, Winner, Kirsten, Schrauder, Michael G, Fasching, Peter A, Anzeneder, Tobias, Veeck, Jürgen, Hartmann, Arndt, Knüchel, Ruth, Dahl, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672828/
https://ncbi.nlm.nih.gov/pubmed/23320751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3375
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