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The C2 Domains of Human Synaptotagmin 1 Have Distinct Mechanical Properties
Synaptotagmin 1 (Syt1) is the Ca(+2) receptor for fast, synchronous vesicle fusion in neurons. Because membrane fusion is an inherently mechanical, force-driven event, Syt1 must be able to adapt to the energetics of the fusion apparatus. Syt1 contains two C2 domains (C2A and C2B) that are homologous...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716670/ https://ncbi.nlm.nih.gov/pubmed/19186144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.025 |
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