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Negative Coupling as a Mechanism for Signal Propagation between C2 Domains of Synaptotagmin I

Synaptotagmin I (Syt I) is a vesicle-localized protein implicated in sensing the calcium influx that triggers fast synchronous release of neurotransmitter. How Syt I utilizes its two C2 domains to integrate signals and mediate neurotransmission has continued to be a controversial area of research, t...

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Bibliografische gegevens
Hoofdauteurs: Fealey, Michael E., Gauer, Jacob W., Kempka, Sarah C., Miller, Katie, Nayak, Kamakshi, Sutton, R. Bryan, Hinderliter, Anne
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465270/
https://ncbi.nlm.nih.gov/pubmed/23071627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046748
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