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Structural Impact of Phosphorylation and Dielectric Constant Variation on Synaptotagmin’s IDR
We used time-resolved Förster resonance energy transfer, circular dichroism, and molecular dynamics simulation to investigate the structural dependence of synaptotagmin 1’s intrinsically disordered region (IDR) on phosphorylation and dielectric constant. We found that a peptide corresponding to the...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985037/ https://ncbi.nlm.nih.gov/pubmed/29414700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.12.013 |
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