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Negative Coupling as a Mechanism for Signal Propagation between C2 Domains of Synaptotagmin I
Synaptotagmin I (Syt I) is a vesicle-localized protein implicated in sensing the calcium influx that triggers fast synchronous release of neurotransmitter. How Syt I utilizes its two C2 domains to integrate signals and mediate neurotransmission has continued to be a controversial area of research, t...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465270/ https://ncbi.nlm.nih.gov/pubmed/23071627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046748 |
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