The C2 Domains of Human Synaptotagmin 1 Have Distinct Mechanical Properties

Synaptotagmin 1 (Syt1) is the Ca(+2) receptor for fast, synchronous vesicle fusion in neurons. Because membrane fusion is an inherently mechanical, force-driven event, Syt1 must be able to adapt to the energetics of the fusion apparatus. Syt1 contains two C2 domains (C2A and C2B) that are homologous...

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Detaylı Bibliyografya
Asıl Yazarlar: Fuson, Kerry L., Ma, Liang, Sutton, R. Bryan, Oberhauser, Andres F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2009
Konular:
Protein
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716670/
https://ncbi.nlm.nih.gov/pubmed/19186144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.025
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