Caricamento...

Probing the role of the cation–π interaction in the binding sites of GPCRs using unnatural amino acids

We describe a general application of the nonsense suppression methodology for unnatural amino acid incorporation to probe drug–receptor interactions in functional G protein-coupled receptors (GPCRs), evaluating the binding sites of both the M2 muscarinic acetylcholine receptor and the D2 dopamine re...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Torrice, Michael M., Bower, Kiowa S., Lester, Henry A., Dougherty, Dennis A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715518/
https://ncbi.nlm.nih.gov/pubmed/19581583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903260106
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !