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Regulation of Interleukin-5–Induced β(2)-Integrin Adhesion of Human Eosinophils by Phosphoinositide 3-Kinase
We examined the role of phosphoinositide 3-kinase (PI3K) in integrin-mediated eosinophil adhesion. Δp85, a dominant-negative form of the class IA PI3K adaptor subunit, was fused to an HIV-TAT protein transduction domain (TAT-Δp85). Recombinant TAT-Δp85 inhibited interleukin (IL)-5–stimulated phospho...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Thoracic Society
2005
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715304/ https://ncbi.nlm.nih.gov/pubmed/15802551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0076OC |
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