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Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury
BACKGROUND: Proline-rich tyrosine kinase 2 (Pyk2) is essential in neutrophil degranulation and chemotaxis in vitro. However, its effect on the process of lung inflammation and edema formation during LPS induced acute lung injury (ALI) remains unknown. The goal of the present study was to determine t...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3275485/ https://ncbi.nlm.nih.gov/pubmed/22257498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-13-4 |
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