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Proline-Rich Tyrosine Kinase 2 Regulates Spreading and Migration of Eosinophils after β(2)-Integrin Adhesion

We examined the role of proline-rich tyrosine kinase (Pyk) 2 in the spreading and migration of human blood eosinophils after β(2)-integrin ligation. Western blot analysis showed that Pyk2 was activated by phosphorylation at Y402 after eosinophil adhesion to BSA-coated plates after activation with IL...

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Bibliografski detalji
Glavni autori: Zhu, Xiangdong, Boetticher, Evan, Wang, Lin, Duan, Yingli, Learoyd, Jonathan, Leff, Alan R.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542445/
https://ncbi.nlm.nih.gov/pubmed/18367725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0047OC
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