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Secretory group V phospholipase A(2) regulates acute lung injury and neutrophilic inflammation caused by LPS in mice

We investigated the regulatory role of 14-kDa secretory group V phospholipase A(2) (gVPLA(2)) in the development of acute lung injury (ALI) and neutrophilic inflammation (NI) caused by intratracheal administration of LPS. Experiments were conducted in gVPLA(2) knockout (pla2g5(−/−)) mice, which lack...

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Bibliografiset tiedot
Päätekijät: Muñoz, Nilda M., Meliton, Angelo Y., Meliton, Lucille N., Dudek, Steven M., Leff, Alan R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2009
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692807/
https://ncbi.nlm.nih.gov/pubmed/19286925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90580.2008
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