Group V phospholipase A(2) increases pulmonary endothelial permeability through direct hydrolysis of the cell membrane

Acute lung injury (ALI) is characterized by inflammatory disruption of the alveolar–vascular barrier, resulting in severe respiratory compromise. Inhibition of the intercellular messenger protein, Group V phospholipase A(2) (gVPLA(2)), blocks vascular permeability caused by LPS both in vivo and in v...

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Detalhes bibliográficos
Main Authors: Muñoz, Nilda M., Desai, Anjali, Meliton, Lucille N., Meliton, Angelo Y., Zhou, Tingting, Leff, Alan R., Dudek, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401872/
https://ncbi.nlm.nih.gov/pubmed/22837859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.97604
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