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The GW182 protein family in animal cells: New insights into domains required for miRNA-mediated gene silencing

GW182 family proteins interact directly with Argonaute proteins and are required for miRNA-mediated gene silencing in animal cells. The domains of the GW182 proteins have recently been studied to determine their role in silencing. These studies revealed that the middle and C-terminal regions functio...

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Hlavní autoři: Eulalio, Ana, Tritschler, Felix, Izaurralde, Elisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714752/
https://ncbi.nlm.nih.gov/pubmed/19535464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1703809
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