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A C-terminal silencing domain in GW182 is essential for miRNA function
Proteins of the GW182 family are essential for miRNA-mediated gene silencing in animal cells; they interact with Argonaute proteins (AGOs) and are required for both the translational repression and mRNA degradation mediated by miRNAs. To gain insight into the role of the GW182–AGO1 interaction in si...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685512/ https://ncbi.nlm.nih.gov/pubmed/19383769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1605509 |
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