MicroRNA-155 Suppresses Activation-Induced Cytidine Deaminase-Mediated Myc-Igh Translocation

MicroRNAs (miRNAs) are small noncoding RNAs that regulate vast networks of genes that share miRNA target sequences. To examine the physiologic effects of an individual miRNA-mRNA interaction in vivo, we generated mice that carry a mutation in the putative microRNA-155 (miR-155) binding site in the 3...

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Autors principals: Dorsett, Yair, McBride, Kevin M., Jankovic, Mila, Gazumyan, Anna, Thai, To-Ha, Robbiani, Davide F., Di Virgilio, Michela, San-Martin, Bernardo Reina, Heidkamp, Gordon, Schwickert, Tanja A., Eisenreich, Thomas, Rajewsky, Klaus, Nussenzweig, Michel C.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713656/
https://ncbi.nlm.nih.gov/pubmed/18455451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.04.002
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