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Synergistic benefit in inflammatory arthritis by targeting IκB kinase ε and interferon β

OBJECTIVES: The IκB kinase (IKK)-related kinase IKKε regulates type I interferon expression and responses as well as proinflammatory mediator production. We examined the role of IKKε in arthritis and its ability to enhance the therapeutic response to systemic interferon (IFN) β therapy in passive mu...

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Autors principals: Corr, M, Boyle, D L, Ronacher, L, Flores, N, Firestein, G S
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713581/
https://ncbi.nlm.nih.gov/pubmed/18653628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2008.095356
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