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Synergistic benefit in inflammatory arthritis by targeting IκB kinase ε and interferon β
OBJECTIVES: The IκB kinase (IKK)-related kinase IKKε regulates type I interferon expression and responses as well as proinflammatory mediator production. We examined the role of IKKε in arthritis and its ability to enhance the therapeutic response to systemic interferon (IFN) β therapy in passive mu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713581/ https://ncbi.nlm.nih.gov/pubmed/18653628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2008.095356 |
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