Загрузка...

Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-Terminal kinase pathway

INTRODUCTION: The c-Jun N-terminal kinase (JNK) is a key regulator of matrix metalloproteinase (MMP) and cytokine production in rheumatoid arthritis (RA) and JNK deficiency markedly protects mice in animal models of arthritis. Cytokine-induced JNK activation is strictly dependent on the mitogen-acti...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Lee, Sang-il, Boyle, David L, Berdeja, Andres, Firestein, Gary S
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392838/
https://ncbi.nlm.nih.gov/pubmed/22353730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3750
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!