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ATP Regulation of Type-1 Inositol 1,4,5-Trisphosphate Receptor Activity Does Not Require Walker A-type ATP-binding Motifs

ATP is known to increase the activity of the type-1 inositol 1,4,5-trisphosphate receptor (InsP(3)R1). This effect is attributed to the binding of ATP to glycine rich Walker A-type motifs present in the regulatory domain of the receptor. Only two such motifs are present in neuronal S2+ splice varian...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Betzenhauser, Matthew J., Wagner, Larry E., Park, Hyung Seo, Yule, David I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713511/
https://ncbi.nlm.nih.gov/pubmed/19386591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006452
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