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ATP Modulation of Ca(2+) Release by Type-2 and Type-3 Inositol (1, 4, 5)-Triphosphate Receptors: DIFFERING ATP SENSITIVITIES AND MOLECULAR DETERMINANTS OF ACTION

ATP enhances Ca(2+) release from inositol (1,4,5)-trisphosphate receptors (InsP(3)R). However, the three isoforms of InsP(3)R are reported to respond to ATP with differing sensitivities. Ca(2+) release through InsP(3)R1 is positively regulated at lower ATP concentrations than InsP(3)R3, and InsP(3)R...

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Detalhes bibliográficos
Main Authors: Betzenhauser, Matthew J., Wagner, Larry E., Iwai, Miwako, Michikawa, Takayuki, Mikoshiba, Katsuhiko, Yule, David I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490775/
https://ncbi.nlm.nih.gov/pubmed/18505727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801680200
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