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The Type 2 Inositol (1,4,5)-Trisphosphate (InsP(3)) Receptor Determines the Sensitivity of InsP(3)-induced Ca(2+) Release to ATP in Pancreatic Acinar Cells
Calcium release through inositol (1,4,5)-trisphosphate receptors (InsP(3)R) is the primary signal driving digestive enzyme and fluid secretion from pancreatic acinar cells. The type 2 (InsP(3)R2) and type 3 (InsP(3)R3) InsP(3)R are the predominant isoforms expressed in acinar cells and are required...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533790/ https://ncbi.nlm.nih.gov/pubmed/18658132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804184200 |
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