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Region-specific proteolysis differentially regulates type 1 inositol 1,4,5-trisphosphate receptor activity
The inositol 1,4,5 trisphosphate receptor (IP(3)R) is an intracellular Ca(2+) release channel expressed predominately on the membranes of the endoplasmic reticulum. IP(3)R1 can be cleaved by caspase or calpain into at least two receptor fragments. However, the functional consequences of receptor fra...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512067/ https://ncbi.nlm.nih.gov/pubmed/28526746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.789917 |
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