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Enzyme (Re)Design: Lessons from Natural Evolution and Computation
The (re)design of enzymes to catalyze “new” reactions is a topic of considerable practical and intellectual interest. Directed evolution (random mutagenesis followed by screening/selection) has been used widely to identify novel biocatalysts. However, “rational” approaches using either natural diver...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711627/ https://ncbi.nlm.nih.gov/pubmed/19237310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2009.01.014 |
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