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Enzyme (Re)Design: Lessons from Natural Evolution and Computation

The (re)design of enzymes to catalyze “new” reactions is a topic of considerable practical and intellectual interest. Directed evolution (random mutagenesis followed by screening/selection) has been used widely to identify novel biocatalysts. However, “rational” approaches using either natural diver...

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Detaylı Bibliyografya
Asıl Yazarlar: Gerlt, John A., Babbitt, Patricia C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711627/
https://ncbi.nlm.nih.gov/pubmed/19237310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2009.01.014
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