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Lessons in Protein Design from Combined Evolution and Conformational Dynamics

Protein-protein interactions play important roles in the control of every cellular process. How natural selection has optimized protein design to produce molecules capable of binding to many partner proteins is a fascinating problem but not well understood. Here, we performed a combinatorial analysi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tripathi, Swarnendu, Waxham, M. Neal, Cheung, Margaret S., Liu, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585694/
https://ncbi.nlm.nih.gov/pubmed/26388515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14259
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