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Urea Impedes the Hydrophobic Collapse of Partially Unfolded Proteins

Proteins are denatured in aqueous urea solution. The nature of the molecular driving forces has received substantial attention in the past, whereas the question how urea acts at different phases of unfolding is not yet well understood at the atomic level. In particular, it is unclear whether urea ac...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stumpe, Martin C., Grubmüller, Helmut
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711416/
https://ncbi.nlm.nih.gov/pubmed/19413980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.051
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