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A pre-existing hydrophobic collapse in the unfolded state of an ultrafast folding protein

Insights into the conformational passage of a polypeptide chain across its free energy landscape have come from the judicious combination of experimental studies and computer simulations(1,2). Even though some unfolded and partially folded proteins are now known to possess biological function(3) or...

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Detalhes bibliográficos
Main Authors: Mok, K. Hun, Kuhn, Lars T., Goez, Martin, Day, Iain J., Lin, Jasper C., Andersen, Niels H., Hore, P. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870186/
https://ncbi.nlm.nih.gov/pubmed/17429353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05728
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