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Urea Impedes the Hydrophobic Collapse of Partially Unfolded Proteins
Proteins are denatured in aqueous urea solution. The nature of the molecular driving forces has received substantial attention in the past, whereas the question how urea acts at different phases of unfolding is not yet well understood at the atomic level. In particular, it is unclear whether urea ac...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711416/ https://ncbi.nlm.nih.gov/pubmed/19413980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.051 |
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