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An Unusual Hydrophobic Core Confers Extreme Flexibility to HEAT Repeat Proteins
Alpha-solenoid proteins are suggested to constitute highly flexible macromolecules, whose structural variability and large surface area is instrumental in many important protein-protein binding processes. By equilibrium and nonequilibrium molecular dynamics simulations, we show that importin-β, an a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931736/ https://ncbi.nlm.nih.gov/pubmed/20816072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.032 |
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