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Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73

BACKGROUND: The p53 tumor suppressor and its related protein, p73, share a homologous DNA binding domain, and mouse genetics studies have suggested that they have overlapping as well as distinct biological functions. Both p53 and p73 are activated by genotoxic stress to regulate an array of cellular...

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Autori principali: Huang, Vera, Lu, Xin, Jiang, Yong, Wang, Jean YJ
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711048/
https://ncbi.nlm.nih.gov/pubmed/19558638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-7-35
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