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Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73

BACKGROUND: The p53 tumor suppressor and its related protein, p73, share a homologous DNA binding domain, and mouse genetics studies have suggested that they have overlapping as well as distinct biological functions. Both p53 and p73 are activated by genotoxic stress to regulate an array of cellular...

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Detalhes bibliográficos
Main Authors: Huang, Vera, Lu, Xin, Jiang, Yong, Wang, Jean YJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711048/
https://ncbi.nlm.nih.gov/pubmed/19558638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-7-35
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