The tumor suppressor p53 can promote collective cellular migration

Loss of function of the tumor suppressor p53 is known to increase the rate of migration of cells transiting the narrow pores of the traditional Boyden chamber assay. Here by contrast we investigate how p53 impacts the rate of cellular migration within a 2D confluent cell layer and a 3D collagen-embe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: He, Shijie, Carman, Christopher V., Lee, Jung Hyun, Lan, Bo, Koehler, Stephan, Atia, Lior, Park, Chan Young, Kim, Jae Hun, Mitchel, Jennifer A., Park, Jin-Ah, Butler, James P., Lu, Quan, Fredberg, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358060/
https://ncbi.nlm.nih.gov/pubmed/30707705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202065
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