The tumor suppressor p53 can promote collective cellular migration

Loss of function of the tumor suppressor p53 is known to increase the rate of migration of cells transiting the narrow pores of the traditional Boyden chamber assay. Here by contrast we investigate how p53 impacts the rate of cellular migration within a 2D confluent cell layer and a 3D collagen-embe...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: He, Shijie, Carman, Christopher V., Lee, Jung Hyun, Lan, Bo, Koehler, Stephan, Atia, Lior, Park, Chan Young, Kim, Jae Hun, Mitchel, Jennifer A., Park, Jin-Ah, Butler, James P., Lu, Quan, Fredberg, Jeffrey J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358060/
https://ncbi.nlm.nih.gov/pubmed/30707705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202065
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